HDAC8-IN-4

HDAC8-IN-4

• CAS Number: 1600528-05-9
• UNSPSC Description: HDAC8-IN-4 is a selective inhibitor of HDAC8. HDAC8-IN-4 inhibits HDAC8 and HDAC3 with IC50s of 0.15 and 12 μM[1].
• Target Antigen: HDAC
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hdac8-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=CC(C2=CSC(CSC3=CC=CC=C3)=N2)=C1)NO
• Molecular Weight: 342.44
• References & Citations: [1]Suzuki T, et al. Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors. ChemMedChem. 2014 Mar;9(3):657-64.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported