HDAC8-IN-3
CAT:
804-HY-147934
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC8-IN-3
- CAS Number: 2432825-93-7
- UNSPSC Description: HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines[1].
- Target Antigen: Apoptosis; HDAC
- Type: Reference compound
- Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hdac8-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=NC2=CC=CC=C2S1)CN(C/3=O)C(SC3=C\C4=NC=CC=C4)=O
- Molecular Weight: 396.44
- References & Citations: [1]Upadhyay N, et al. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation. Bioorg Chem. 2020 Jul;100:103934.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported