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Apoptosis inducer 19

CAT: 0804-HY-161659-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161659-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apoptosis inducer 19 (Compound 7g) is an Apoptosis inducer. Apoptosis inducer 19 elevates expression of pro-apoptotic proteins (Bax and caspase-3) and downregulates anti-apoptotic protein (Bcl-2) . Apoptosis inducer 19 upregulates cellular reactive oxygen species (ROS) levels and disrupts mitochondrial membrane potential (MMP) . Apoptosis inducer 19 can be used for triple-negative breast cancer (TNBC) research[1].
CAS Number
3049296-75-2
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-19.html
Purity
98.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
COC1=CC=C(/C=C/C(C2=CC=C(OCC(N3CCCC3)=O)C=C2)=O)C=C1
Molecular Formula
C22H23NO4
Molecular Weight
365.42
References & Citations
[1]Kumar P, et al. Design, synthesis, and biological evaluation of chalcone acetamide derivatives against triple negative breast cancer. Bioorg Med Chem Lett. 2024 Jul 15;107:129795.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2; Caspase 3

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