Apoptosis inducer 30

CAT: 0804-HY-168589Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-168589Size:1 Each
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Description
Apoptosis inducer 30 (Compound 15a) is an anticancer agent. Apoptosis inducer 30 induces MCF-7 cells apoptosis through mitochondrial pathway. Apoptosis inducer 30 induces intracellular reactive oxygen species levels and decreases mitochondrial membrane potential, and blocks the cell cycle in the G0/G1 phase. Apoptosis inducer 30 inhibits cell growth, with an IC50 value of 0.32 μM against MCF-7 cells, and inhibits tumor growth in a mouse model of breast cancer[1].
UNSPSC
12352211
Target
Apoptosis; Caspase; Cytochrome P450; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-30.html
Smiles
CC(C)[C@H](C)/C=C/[C@@H](C)[C@H]1CCC2[C@@]34C=C[C@@]5(OO4)C[C@@H](OC(NCCCCC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)=O)CC[C@]5(C)C3CC[C@@]21C.[Br-]
Molecular Formula
C52H69BrNO4P
Molecular Weight
882.99
References & Citations
[1]Wang L, et al. Design and synthesis of novel mitochondria-targeted ergosterol peroxide derivatives as potential anti-cancer agents. Bioorg Chem. 2024 Oct 1;153:107862.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 7; Caspase 9

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