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SDZ 220-040

CAT: 0804-HY-107704-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107704-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDZ 220-040 is a competitive the mammalian NMDA receptor antagonist with a pKi of 8.5. SDZ 220-040 can be used in the study of neurological diseases[1][2].
CAS Number
174575-40-7
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sdz-220-040.html
Purity
99.14
Smiles
ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)(O)=O)=C2)O
Molecular Formula
C16H16Cl2NO6P
Molecular Weight
420.18
References & Citations
[1]Brian G Forde. et al. Glutamate signalling via a MEKK1 kinase-dependent pathway induces changes in Arabidopsis root architecture. Plant J. 2013 Jul;75 (1) :1-10. |[2]Urwyler S, et al. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35 (6) :655-69.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor