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SDZ-WAG994

CAT: 0804-HY-103179Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103179Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1].
CAS Number
[130714-47-5]
Product Name Alternative
WAG-994; N6-Cyclohexy-2'-0-methyladenosine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sdz-wag994.html
Solubility
10 mM in DMSO
Smiles
CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC4CCCCC4
Molecular Formula
C17H25N5O4
Molecular Weight
363.41
Precautions
H302, H315, H319, H335
References & Citations
[1]O Piot, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21 (11 Pt 2) :2459-64.|[2]Wagner H, et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug development research, 1995, 34 (3) : 276-288.|[3]Piot O, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21 (11 Pt 2) :2459-64.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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