SDZ-WAG994

• UNSPSC Description:

  SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1].

• Target Antigen:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sdz-wag994.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC4CCCCC4

• Molecular Weight:

  363.41

• References & Citations:

  [1]O Piot, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64.|[2]Wagner H, et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug development research, 1995, 34(3): 276-288.|[3]Piot O, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  Phase 1

• CAS Number:

  130714-47-5