SDZ-FOX-988

CAT: 0804-HY-19150Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19150Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDZ-FOX-988 (FOX-988) is an orally active antidiabetic agent. SDZ-FOX-988 sequesters mitochondrial coenzyme A to inhibit carnitine palmitoyltransferase II. SDZ-FOX-988 induces mitochondrial injury. SDZ-FOX-988 causes a decrease in serum β-hydroxybutyrate or glucose. SDZ-FOX-988 can be used in the research of type 2 diabetes[1][2].
CAS Number
[139681-18-8]
Product Name Alternative
FOX-988
UNSPSC
12352005
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(C(C)(C)C)C1=CC=C(/C(OC(C2=CC=C(C(C(C)(C)C)=O)C=C2)=O)=N\OC)C=C1
Molecular Formula
C25H29NO5
Molecular Weight
423.50
References & Citations
[1]Lau DT, et al. The effect of the fat content of food on the pharmacokinetics and pharmacodynamics of SDZ FOX 988, an antidiabetic agent, in the dog. Biopharm Drug Dispos. 1995 Mar;16 (2) :137-50. |[2]Vickers AE, et al. Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices. Toxicol In Vitro. 2006 Oct;20 (7) :1173-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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