U-85548E

• Description:

  U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.

• UNSPSC:

  12352209

• Target:

  HIV Protease

• Type:

  Peptides

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/u-85548e.html

• Smiles:

  CC (C) [C@H] (N) C (N[C@@H] (CO) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CC (N) =O) C (N[C@@H] (CC (C) C) [C@@H] (O) C[C@@H] (C (C) C) C (N[C@@H] ([C@@H] (C) CC) C (N[C@H] (C (O) =O) C (C) C) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C40H73N9O12

• Molecular Weight:

  872.06

• References & Citations:

  [1]HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH (OH) CH2]Val modified viral and nonviral …

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  124020-62-8