U-85548E

• Description :

  U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.

• UNSPSC :

  12352209

• Target :

  HIV Protease

• Type :

  Peptides

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/u-85548e.html

• Smiles :

  CC(C)[C@H](N)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)[C@@H](O)C[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C40H73N9O12

• Molecular Weight :

  872.06

• References & Citations :

  [1]HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH (OH) CH2]Val modified viral and nonviral …

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [124020-62-8]