U-85548E

CAT: 0804-HY-P2138Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P2138Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling.
CAS Number
[124020-62-8]
UNSPSC
12352209
Target
HIV Protease
Type
Peptides
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/u-85548e.html
Smiles
CC(C)[C@H](N)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)[C@@H](O)C[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O
Molecular Formula
C40H73N9O12
Molecular Weight
872.06
References & Citations
[1]HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH (OH) CH2]Val modified viral and nonviral …
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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