Complement Component C3a Recombinant Protein

CAT: 0223-92-689Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-92-689Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.
CAS Number
9000-83-3
NCBI Gene ID
12266
Swiss Prot
P01027
Accession Number
P01027
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
9.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Complement component 3
NCBI Organism
Mus musculus
Other Product Names
Complement Component C3a, Anaphylatoxin, C3a
Species
Mouse
Physical Properties
Lyophilized

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