IGF-1

• Description:

  Insulin-like growth factor (IGF) -I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity.

• Synonyms:

  Igf1; Igf-1; Igf-I; C730016P09Rik

• NCBI Gene ID:

  16000

• UniProt:

  P05017

• Accession Number:

  NP_034642.2

• Accession Number mRNA:

  NM_010512

• Chromosomal Location:

  10 C1; 10 48.0 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Recombinant mouse protein of IGF-I

• Clone:

  (#2F54)

• Applications:

  WB, IHC (P)

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Hamster

• Isotype:

  IgG2