Complement Factor H-related 5 Recombinant Protein

• Background:

  Complement factor H-related protein 5 (FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

• NCBI Gene ID:

  81494

• Swiss Prot:

  Q9BXR6

• Accession Number:

  Q9BXR6

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  63.5 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Complement factor H related 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Complement factor H-related protein 5, CFHR5, CFHL5, FHR5

• Species:

  Human

• Protein ID:

  767932354

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3