Complement Factor B Recombinant Protein

• Background:

  Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

• NCBI Gene ID:

  629

• Swiss Prot:

  P00751

• Accession Number:

  P00751

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  84.07 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Complement factor B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3