Complement factor H Recombinant Protein

CAT: 0223-92-382Size: 0.05 mgDry Ice: YesHazardous: No
CAT#:0223-92-382Size:0.05 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.
CAS Number
9000-83-3
NCBI Gene ID
3075
Swiss Prot
P08603-2
Accession Number
P08603-2
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer
Buffer
Supplied as a 0.2 um filtered solution of PBS,20%Glycerol,5% Trehalose, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
50 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Complement factor H
NCBI Organism
Homo sapiens
Other Product Names
Complement factor H, CFH
Species
Human
Physical Properties
Liquid

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