Complement factor D Recombinant Protein

• Background:

  Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.

• NCBI Gene ID:

  1675

• Swiss Prot:

  P00746

• Accession Number:

  P00746

• Tag:

  C-10 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  25.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Complement factor D (adipsin)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Complement factor D, CFD, Adipsin, C3 convertase activator, Properdin factor D, DF, PFD

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3