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Complement Factor H-related 1 Recombinant Protein

CAT: 0223-91-522Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-522Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5) . Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa) . Mature human FHR1 is 312 amino acids in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.
CAS Number
9000-83-3
NCBI Gene ID
3078
Swiss Prot
Q03591
Accession Number
Q03591
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
36.78 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Complement factor H related 1
NCBI Organism
Homo sapiens
Other Product Names
Complement Factor H-Related Protein 1, FHR-1, H Factor-Like Protein 1, H-Factor-Like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2
Species
Human
Physical Properties
Lyophilized

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