Nav1.8-IN-7

• UNSPSC Description:

  Nav1.8-IN-7 (Example 116) is a selective Nav1.8 inhibitor. Nav1.8-IN-7 shows an inhibition of >50% with 100 nM for Nav1.8. Nav1.8-IN-7 inhibits hERG with an IC50 of 15.6 μM. Nav1.8-IN-7 has the potential for pain research[1].

• Target Antigen:

  Potassium Channel; Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nav1-8-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@@H](O)COC1=CC(NC(C(C=C(C(C(F)(F)F)=C2)Cl)=C2OC3=C(C=C(C=C3)F)C)=O)=CN=N1

• Molecular Weight:

  515.84

• References & Citations:

  [1]Junfeng Ren, et al. A benzylamine or benzyl alcohol derivative and its use. CN114031518A.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2761181-58-0