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Nav1.8-IN-7

CAT: 0931-T86970-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86970-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2761181-58-0
Target
Sodium Channel, Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Nav1.8-IN-7 (Example 116) serves as a selective inhibitor of Nav1.8, demonstrating more than 50% inhibition at 100 nM specifically for Nav1.8. It exhibits an IC50 of 15.6 μM for the hERG channel. This compound holds promise in the field of pain research [1].
Smiles
O(C1=C(C(NC=2C=C(OC[C@@H](CO)O)N=NC2)=O)C=C(Cl)C(C(F)(F)F)=C1)C3=C(C)C=C(F)C=C3
Molecular Formula
C22H18ClF4N3O5
Molecular Weight
515.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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