Nav1.8-IN-7

• Target:

  Sodium Channel|||Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  Nav1.8-IN-7 (Example 116) serves as a selective inhibitor of Nav1.8, demonstrating more than 50% inhibition at 100 nM specifically for Nav1.8. It exhibits an IC50 of 15.6 ?M for the hERG channel. This compound holds promise in the field of pain research [1].

• Smiles:

  O (C1=C (C (NC=2C=C (OC[C@@H] (CO) O) N=NC2) =O) C=C (Cl) C (C (F) (F) F) =C1) C3=C (C) C=C (F) C=C3

• Molecular Formula:

  C22H18ClF4N3O5

• Molecular Weight:

  515.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2761181-58-0