Nav1.8-IN-13

• UNSPSC Description:

  Nav1.8-IN-13 (compound 16) is a Nav1.8 inhibitor (pIC50=7.9)[1].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/nav1-8-in-13.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C=C1)NC(C)=C1N(C2=O)CN(C3=CC=C(OC(F)(F)F)C=C3C)C4=C2C=C(C(F)(F)F)N=C4

• Molecular Weight:

  498.38

• References & Citations:

  [1]Xiaoyang Dong, et al. Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors.US20240083896A1.2021-12-16

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2785391-79-7