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Nav1.8-IN-19

CAT: 0804-HY-172999Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172999Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nav1.8-IN-19 (Compound 122) is a Nav1.8 inhibitor with an IC50 of 0.44 nM in HEK cells. Nav1.8-IN-19 can be used for the study of pain[1].
CAS Number
3003829-05-5
UNSPSC
12352211
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
NS(=O)(C1=NC=CC(NC(C2=CC3=C(N=C2N4CCC(F)([C@H](C4)C)F)C=CC(F)=C3)=O)=C1)=O
Molecular Formula
C21H20F3N5O3S
Molecular Weight
479.48
References & Citations
[1]Jie Zhu, et al. Bicyclic heterocyclic amide inhibitors of na v1.8 for the treatment of pain. WO2023211990A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8

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