COX-1-IN-2

CAT: 0804-HY-159561Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-159561Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

COX-1-IN-2 (compound 5h) is an anti-inflammatory agent with potent analgesic activity. COX-1-IN-2 exhibits a significant inhibitory effect on COX-1 (IC50=38.76 nM) [1].

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-1-in-2.html

Smiles

FC1=CC=C(C2CC(C3=CC=C4C=CC=CC4=C3)=NN2C5=NC(C6=CC=C(OC)C=C6)=CS5)C=C1

Molecular Formula

C29H22FN3OS

Molecular Weight

479.57

References & Citations

[1]Mohammed, et al. "Discovery of new 2- (3- (naphthalen-2-yl) -4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024) : 107372.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

COX-1

Related Products

Catalog	Name
HY-U00275	COX-2-IN-1
HY-146161	COX-2/NO-IN-1
HY-115967	COX-1/2-IN-2
HY-115966	COX-1/2-IN-1
HY-159158	COX-1/2-IN-8
HY-161513	INOS/COX-2-IN-1
HY-162761	COX-1/2-IN-9
HY-155764	COX-1/2-IN-4
HY-163187	COX-2/LOX-IN-1
HY-170932	EGFR/COX-2-IN-1

Alternative Products

Catalog	Name
T60403-01	COX-2/NO-IN-1
T10033-01	COX-2-IN-1
GTR19239148-01	COX-1-IN-2
T61865-01	COX-1/2-IN-2
GTR19187365-01	COX-1/2-IN-1
TBS2121	Cyclooxygenase (COX-1, COX-2) Inhibition Assay
T209169-01	COX-2/LOX-IN-1
T63398-01	COX-2/sEH-IN-1
T79594-01	COX-1/2-IN-5
MBS5803705	COX-1/2-IN-3

COX-1-IN-2

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