COX-1-IN-2

• UNSPSC Description:

  COX-1-IN-2 (compound 5h) is an anti-inflammatory agent with potent analgesic activity. COX-1-IN-2 exhibits a significant inhibitory effect on COX-1 (IC50=38.76 nM)[1].

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cox-1-in-2.html

• Smiles:

  FC1=CC=C(C2CC(C3=CC=C4C=CC=CC4=C3)=NN2C5=NC(C6=CC=C(OC)C=C6)=CS5)C=C1

• Molecular Weight:

  479.57

• References & Citations:

  [1]Mohammed, et al. "Discovery of new 2-(3-(naphthalen-2-yl)-4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024): 107372.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported