COX-1/2-IN-1

COX-1/2-IN-1

• CAS Number: 2358849-47-3
• UNSPSC Description: COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 13.9 ± 3.21 µM and 6.4±0.74 µM, respectively[1].
• Target Antigen: COX
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cox-1-2-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=[N+]([O-])C(C2=CC=C(Cl)C=C2)=NC3=CC=C(Br)C=C13
• Molecular Weight: 349.61
• References & Citations: [1]Malose J. Mphahlele, et al. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides. Medicinal Chemistry Research volume 31, pages146–164 (2022)
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported