COX-1/2-IN-2
CAT:
804-HY-115967
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
COX-1/2-IN-2
- CAS Number: 2882832-86-0
- UNSPSC Description: COX-1/2-IN-2 is a potent COX1/2 inhibitor. COX-1/2-IN-2 exhibits significant inhibitory effect against COX-1 and COX-2 inhibitor with IC50 values of 9.7 ± 0.09 µM and 4.6 ± 1.45 µM, respectively[1].
- Target Antigen: COX
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/cox-1-2-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=[N+](C(C2=CC=C(C=C2)Cl)=NC3=CC=C(C=C31)I)[O-]
- Molecular Weight: 396.61
- References & Citations: [1]Malose J. Mphahlele, et al. Synthesis, in vitro and in silico enzyme (COX-1/2 & LOX-5), free radical scavenging and cytotoxicity profiling of the 2,4-dicarbo substituted quinazoline 3-oxides. Medicinal Chemistry Research volume 31, pages146–164 (2022)
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported