BJH-60

• Description :

  BJH-60 is a mitochondrial complex 1 inhibitor. BJH-60 can inhibit mitochondrial oxygen consumption rate with an IC50 of 1.9 μM in A549 cells. BJH-60 shows no PDE inhibitory effect. BJH-60 can be used for the research of cancer, such as breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Mitochondrial Metabolism

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  OCC1=CC=C(C2=CC=CC(CC3=CC=NC4=CC=C(OC)C=C34)=C2)C=C1

• Molecular Formula :

  C24H21NO2

• Molecular Weight :

  355.43

• References & Citations :

  [1]Haines BJ, et al. Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer. J Med Chem. 2025;68 (21) :23140-23162.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3067849-06-0]