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BChE-IN-30

CAT: 0804-HY-162339Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162339Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BChE-IN-30 (compound (R) -37a) is a BChE inhibitor (IC50: 5 nM) with anti-inflammatory activity and low toxicity. BChE-IN-30 can improve cognitive deficits induced by scopolamine and Aβ1-42 peptide and can be used in the study of late-stage AD[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-30.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C(N(CCC)CCC)=O)C=C1S(N[C@H](C)CN2CCCCCC2)(=O)=O
Molecular Formula
C23H39N3O3S
Molecular Weight
437.64
References & Citations
[1]Lu X, et al. Discovery, Structure-Based Modification, In Vitro, In Vivo, and In Silico Exploration of m-Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS Chem Neurosci. 2024 Mar 7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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