Ac-QPKK(Ac)-AMC

• UNSPSC Description:

  Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin through sirtuin deacetylation[1].

• Target Antigen:

  Sirtuin

• Type:

  Peptides

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ac-qpkk-ac-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCCNC(C)=O)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](NC(C)=O)CCC(N)=O)=O)=O)=O)=O)C=C1O3)=CC3=O

• Molecular Weight:

  740.85

• References & Citations:

  [1]Galleano I, et al., A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation. J Med Chem. 2016 Feb 11;59(3):1021-31.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1387005-23-3