Ac-DNLD-AMC

CAT: 0804-HY-P3110Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P3110Size:1 mg
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Description
Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity[1][2].
CAS Number
[958001-92-8]
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-dnld-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O)=CC1=O
Molecular Formula
C30H38N6O12
Molecular Weight
674.66
References & Citations
[1]Kulikov AV, et al. Targeting mitochondria by α-tocopheryl succinate overcomes hypoxia-mediated tumor cell resistance to treatment. Cell Mol Life Sci. 2014 Jun;71 (12) :2325-33.|[2]Yoshida K, et al. Caspase-independent cell death without generation of reactive oxygen species in irradiated MOLT-4 human leukemia cells. Cell Immunol. 2009;255 (1-2) :61-8.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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