Ac-PAL-AMC

CAT: 0931-T37421-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T37421-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1431362-79-6

Target

Others, Proteasome

Related Pathways

Others, Ubiquitination, Proteases/Proteasome

Bioactivity

Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the β1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.

Smiles

CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC(=O)[C@H]3N(C(C)=O)CCC3)C)=O)CC(C)C)=O)=CC2)OC(=O)C1

Molecular Formula

C26H34N4O6

Molecular Weight

498.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
BA8292-5	Ac-PAL-AMC
13467-AAT	(Ac-PAL) 2R110
HY-P11213	Ac-RYQK (Ac) -AMC
HY-P11212	Ac-RHKK (Ac) -AMC
HY-P3364-01	Ac-QPKK (Ac) -AMC
BA4167-5.1	Ac-Lys-AMC
C8322-5	Ac-YEVD-AMC
4028557.0050	Ac-Met-AMC
I-1830.0050	Ac-Ala-AMC
HY-P10082	Ac-VETD-AMC

Ac-PAL-AMC

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