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Ac-LEHD-AMC

CAT: 0804-HY-D1652-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D1652-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm) . Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].
CAS Number
292633-16-0
UNSPSC
12171500
Target
Caspase
Type
Dye Reagents
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-lehd-amc.html
Purity
98.96
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C33H41N7O11
Molecular Weight
711.72
References & Citations
[1]Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151 (3) :299-316.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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