JTK-101

• UNSPSC Description:

  JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1].

• Target Antigen:

  CDK; HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Cell Cycle/DNA Damage

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/jtk-101.html

• Smiles:

  N#CC1=CC=C(C=C1)CN2CCC(CC2)(OC3=C4C=C(C=CC4=CC=C35)OC)NC5=O

• Molecular Weight:

  413.47

• References & Citations:

  [1]Wang X, et al. Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101. Antivir Chem Chemother. 2007;18(4):201-11.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  503048-34-8