JTK-109
CAT:
804-HY-19643
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JTK-109
- CAS Number: 480462-62-2
- UNSPSC Description: JTK-109 is a potent inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase. JTK-109 has NS5B inhibitory activity with IC50 value of 0.017μM. JTK-109 can be used for the research of hepatitis C virus (HCV) [1].
- Target Antigen: HCV Protease
- Type: Reference compound
- Related Pathways: Anti-infection;Metabolic Enzyme/Protease
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/jtk-109.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC=C2C(N=C(C3=CC=C(OCC4=CC(N5C(CCC5)=O)=CC=C4C6=CC=C(Cl)C=C6)C=C3F)N2C7CCCCC7)=C1)O
- Molecular Weight: 638.13
- References & Citations: [1]Hirashima S, et al. Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3181-6.
- Shipping Conditions: Room temperature
- Clinical Information: Phase 1