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KUC-7322

CAT: 0804-HY-116169Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116169Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KUC-7322, a selective β3 -adrenoceptor agonist, is the active form of ritobegron. Ritobegron decreases intravesical pressure with minimal effects on the cardiovascular system.
CAS Number
255734-04-4
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kuc-7322.html
Solubility
10 mM in DMSO
Smiles
O=C(COC1=CC(C)=C(C=C1C)CCN[C@H]([C@@H](C2=CC=C(C=C2)O)O)C)O
Molecular Formula
C21H27NO5
Molecular Weight
373.44
References & Citations
[1]Igawa Y, Schneider T, Yamazaki Y, et al. Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322. Naunyn Schmiedebergs Arch Pharmacol. 2012;385 (8) :759-767.|[2]Abe Y, Nakano Y, Kanazawa T, Furihata T, Endo T, Kobayashi M. Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β3 -Adrenoceptor Agonist, With Probenecid in Healthy Men. Clin Pharmacol Drug Dev. 2016;5 (3) :201-207.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
β adrenergic receptor

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