Products for Research Use Only
RegisterLogin

CPPG

CAT: 0804-HY-101333-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101333-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CPPG ((RS) -CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1].
CAS Number
183364-82-1
Product Name Alternative
(RS) -CPPG
UNSPSC
12352005
Hazard Statement
H302
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cppg.html
Purity
99.0
Smiles
O=C(O)C(C1CC1)(N)C2=CC=C(P(O)(O)=O)C=C2
Molecular Formula
C11H14NO5P
Molecular Weight
271.21
Precautions
H302
References & Citations
[1]Toms NJ, et al. The effects of (RS) -alpha-cyclopropyl-4-phosphonophenylglycine ((RS) -CPPG), a potent and selective metabotropic glutamate receptor antagonist. Br J Pharmacol. 1996 Nov;119 (5) :851-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR

Chemical Information

(RS)-alpha-cyclopropyl-4-phosphonophenylglycine

2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.

CAS Number183364-82-1
PubChem CID2878
IUPAC Name2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid
Molecular FormulaC11H14NO5P
Molecular Weight271.21
XLogP-3.1
Topological Polar Surface Area121
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count18
Formal Charge0
Complexity383
SMILES
C1CC1C(C2=CC=C(C=C2)P(=O)(O)O)(C(=O)O)N
InChI
InChI=1S/C11H14NO5P/c12-11(10(13)14,7-1-2-7)8-3-5-9(6-4-8)18(15,16)17/h3-7H,1-2,12H2,(H,13,14)(H2,15,16,17)
InChIKey
IGODGTDUQSMDQU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine
CAS: 183364-82-1
CID: 2878
Formula: C11H14NO5P
MW: 271.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight271.21
XLogP3-3.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass271.06095954
Monoisotopic Mass271.06095954
Topological Polar Surface Area121 Ų
Heavy Atom Count18
Formal Charge0
Complexity383
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-P4090CPP2
HY-P10644CPP9
HY-W728085-01CPPD-Q
HY-P10644A-01CPP9 (TFA)
HY-P11072-01IRF5-CPP5
HY-173549CPPA-TPP
HY-123814-014-CPPC
HY-116910CPP-115
HY-P11207NLS-CPP
HY-100814-01(R) -CPP

Alternative Products

CatalogName
T10880-01CPPG
sc-203448A(RS) -CPPG
TRC-R683003-100MGrac-CPPG

Popular Products