CPPG

CAT: 0804-HY-101333-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101333-01Size:1 mg
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Description
CPPG ((RS) -CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1].
CAS Number
[183364-82-1]
Product Name Alternative
(RS) -CPPG
UNSPSC
12352005
Hazard Statement
H302
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cppg.html
Purity
99.0
Smiles
O=C(O)C(C1CC1)(N)C2=CC=C(P(O)(O)=O)C=C2
Molecular Formula
C11H14NO5P
Molecular Weight
271.21
Precautions
H302
References & Citations
[1]Toms NJ, et al. The effects of (RS) -alpha-cyclopropyl-4-phosphonophenylglycine ((RS) -CPPG), a potent and selective metabotropic glutamate receptor antagonist. Br J Pharmacol. 1996 Nov;119 (5) :851-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR

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