CPP-115

• Description :

  CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399) . CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms[1].

• UNSPSC :

  12352211

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cpp-115.html

• Smiles :

  OC([C@H]1C/C([C@H](C1)N)=C(F)\F)=O

• Molecular Formula :

  C7H9F2NO2

• Molecular Weight :

  177.15

• References & Citations :

  [1]Silverman R B, et al. The 2011 EB Hershberg Award for important discoveries in medicinally active substances: (1 S, 3 S) -3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a GABA aminotransferase inactivator and new treatment for drug addiction and infantile spasms[J]. Journal of medicinal chemistry, 2012, 55 (2) : 567-575.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [640897-20-7]