STING18

• Description :

  STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.

• CAS Number :

  [2706536-26-5]

• Product Name Alternative :

  Stimulator of interferon genes 18

• UNSPSC :

  12352005

• Target :

  STING

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/sting18.html

• Purity :

  98.60

• Solubility :

  DMF : 10 mg/mL (ultrasonic; warming)

• Smiles :

  O=C(CC1C2=CC=C(C=C2C(N(C1C3=CC=C4OCCOC4=C3)C5=CC=C(C(C)(C)C)C(Cl)=C5)=O)F)O

• Molecular Formula :

  C29H27ClFNO5

• Molecular Weight :

  523.98

• References & Citations :

  [1]Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1