sulfo-SPDB

• UNSPSC Description:

  sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sulfo-spdb.html

• Purity:

  95.0

• Solubility:

  DMSO : ≥ 125 mg/mL

• Smiles:

  O=C(ON1C(CCC1=O)=O)C(S(=O)(O)=O)CCSSC2=NC=CC=C2

• Molecular Weight:

  406.45

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C, protect from light, stored under nitrogen

• Clinical Information:

  No Development Reported

• CAS Number:

  1193111-39-5