DMAC-SPDB-sulfo

CAT: 0804-HY-131084Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-131084Size:1 Each
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Description
DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
[663599-07-3]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dmac-spdb-sulfo.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=C(C(N(C)C)=O)C=C2
Molecular Formula
C16H19N3O8S3
Molecular Weight
477.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker

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