NO2-SPDB-sulfo

• UNSPSC Description:

  NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/no2-spdb-sulfo.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=C([N+]([O-])=O)C=C2

• Molecular Weight:

  451.45

• References & Citations:

  [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  663598-89-8