NO2-SPDB-sulfo

NO2-SPDB-sulfo

• CAS Number: 663598-89-8
• UNSPSC Description: NO2-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/no2-spdb-sulfo.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=C([N+]([O-])=O)C=C2
• Molecular Weight: 451.45
• References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported