SPDB-sulfo

• Description :

  SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].

• UNSPSC :

  12352203

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/spdb-sulfo.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=CC=C2

• Molecular Formula :

  C13H14N2O7S3

• Molecular Weight :

  406.45

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Tinya Abrams, et al. ANTIBODY DRUG CONUGATES. US20140271688A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Disulfide Cleavable Linker

• CAS Number :

  [1628113-16-5]