SPDB-sulfo

• Description:

  SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/spdb-sulfo.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=CC=C2

• Molecular Formula:

  C13H14N2O7S3

• Molecular Weight:

  406.45

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Tinya Abrams, et al. ANTIBODY DRUG CONUGATES. US20140271688A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Disulfide Cleavable Linker

• CAS Number:

  [1628113-16-5]