KR-12 (human)

CAT: 0804-HY-P10257-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P10257-01Size:1 mg
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Description
KR-12 (human) is an active segment of LL-37 (HY-P4744) . KR-12 (human) exhibits antimicrobial activity against gram-negative bacteria. KR-12 (human) inhibits E. coli K-12 with a MIC of 66 μM. KR-12 human can be used for the research of infection, such as E. coli infection[1].
CAS Number
[1218951-51-9]
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kr-12-human.html
Purity
99.91
Solubility
H2O : ≥ 100 mg/mL
Smiles
NCCCC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C71H127N25O15
Molecular Weight
1570.93
References & Citations
[1]Epand RF, et al., Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37. Antimicrob Agents Chemother. 2009 Sep;53 (9) :3705-14.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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CatalogName
M40001-01KR-12 (human)
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