EZH2-IN-19

• Description :

  EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research[1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ezh2-in-19.html

• Smiles :

  CCN(C1CCC(CC1)N(C)C)C2=CC(C3=CC=C4C(N(C(N4C5CCN(C)CC5)=O)C)=C3)=CC(C(NCC6=C(C=C(NC6=O)C)C)=O)=C2C

• Molecular Formula :

  C40H55N7O3

• Molecular Weight :

  681.91

• References & Citations :

  [1]Di Wu, et al. Discovery of novel pyridone-benzamide derivatives possessing a 1-methyl-2-benzimidazolinone moiety as potent EZH2 inhibitors for the treatment of B-cell lymphomas. Bioorg Med Chem. 2024 May 1:105:117725.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EZH2

• CAS Number :

  [3026848-13-2]