CHIR-2279

• Description:

  CHIR-2279 is a high-affinity ligand (Ki=5 nM) for the α1-adrenergic receptor and can be further studied as a drug lead compound[1].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/chir-2279.html

• Smiles:

  O=C (CN (CCC1=CC=CC=C1) C (CN (C (CNCCC2=CC=C (C=C2) O) =O) C3=CC=C (C4=CC=CC=C4) C=C3) =O) N

• Molecular Formula:

  C34H36N4O4

• Molecular Weight:

  564.67

• References & Citations:

  [1]Zuckermann, et al. Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N- (substituted) glycine peptoid library. Journal of medicinal chemistry 37.17 (1994) : 2678-2685.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  α adrenergic receptor

• CAS Number:

  158198-45-9