DAT-582

• Description :

  DAT-582 is a serotonin 3 (5-HT3) receptor antagonist that has an antiemetic effect[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dat-582.html

• Smiles :

  CC1=CC=CC(CN(CCN(C2)C)C[C@@H]2NC(C3=NNC4=CC=CC=C34)=O)=C1.Cl.Cl

• Molecular Formula :

  C22H29Cl2N5O

• Molecular Weight :

  450.40

• References & Citations :

  [1]Yoshida N, et al. DAT-582, a novel serotonin3 receptor antagonist, is a potent and long-lasting antiemetic agent in the ferret and dog. J Pharmacol Exp Ther. 1992 Mar;260 (3) :1159-65.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [141034-42-6]