DAT-582

• Description:

  DAT-582 is a serotonin 3 (5-HT3) receptor antagonist that has an antiemetic effect[1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dat-582.html

• Smiles:

  CC1=CC=CC (CN (CCN (C2) C) C[C@@H]2NC (C3=NNC4=CC=CC=C34) =O) =C1.Cl.Cl

• Molecular Formula:

  C22H29Cl2N5O

• Molecular Weight:

  450.40

• References & Citations:

  [1]Yoshida N, et al. DAT-582, a novel serotonin3 receptor antagonist, is a potent and long-lasting antiemetic agent in the ferret and dog. J Pharmacol Exp Ther. 1992 Mar;260 (3) :1159-65.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  141034-42-6