RK-582

• Target :

  PARP|||Others

• Related Pathways :

  Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair

• Bioactivity :

  RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

• Smiles :

  O=C1C2(C=3C(N1C)=CC(=CC3F)N4C[C@@H](C)O[C@@H](C)C4)CCN(CC2)C=5NC6=C(C(=O)N5)CCCN6C

• Molecular Formula :

  C27H35FN6O3

• Molecular Weight :

  510.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2171388-28-4