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RK-582

CAT: 0931-T69839-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69839-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2171388-28-4
Target
PARP, Others
Related Pathways
Chromatin/Epigenetic, Others, DNA Damage/DNA Repair
Bioactivity
RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.
Smiles
O=C1C2(C=3C(N1C)=CC(=CC3F)N4C[C@@H](C)O[C@@H](C)C4)CCN(CC2)C=5NC6=C(C(=O)N5)CCCN6C
Molecular Formula
C27H35FN6O3
Molecular Weight
510.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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