RK-582

• Target:

  PARP|||Others

• Related Pathways:

  Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair

• Bioactivity:

  RK-582 is an orally efficacious spiroindolinone-based tankyrase inhibitor for the treatment of colon cancer. It exhibits a markedly improved robust tumor growth inhibition in a COLO-320DM mouse xenograft model when orally administered.

• Smiles:

  O=C1C2 (C=3C (N1C) =CC (=CC3F) N4C[C@@H] (C) O[C@@H] (C) C4) CCN (CC2) C=5NC6=C (C (=O) N5) CCCN6C

• Molecular Formula:

  C27H35FN6O3

• Molecular Weight:

  510.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2171388-28-4