DAT-230

DAT-230

• CAS Number: 1504583-00-9
• UNSPSC Description: DAT-230 is a microtubule inhibitor. DAT-230 induces cell apoptosis and results in microtubule de-polymerization and G2/M phase arrest. DAT-230 inhibits cell growth in vitro and in vivo[1][2].
• Target Antigen: Apoptosis; Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dat-230.html
• Smiles: NC1=CC(C2=C(C3=CC(C)=C(C)C(OC)=C3)SC=C2)=CC=C1OC
• Molecular Weight: 339.45
• References & Citations: [1]Qiao F, et al. DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells. Biol Pharm Bull. 2013;36(2):193-201. |[2]Tang J, et al. Application of an ultra-performance liquid chromatography method with tandem mass spectrometry to pharmacokinetics, tissue distribution and excretion in the study of DAT-230, a novel tubulin-binding agent candidate, in rats. J Pharm Biomed Anal. 2015;110:49-57.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported