DAT-IN-1

• Description :

  DAT-IN-1 (Coumpound 12b) is an atypical DAT inhibitor with a Ki of 8.37 nM. DAT-IN-1 can be used in the study of psychostimulant use disorder (PSUD) [1].

• UNSPSC :

  12352005

• Target :

  Dopamine Transporter

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/dat-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC1=CC=C(C(C2=CC=C(C=C2)F)S(CCN3CCCN(CC3)CC(CC4=CC=CC=C4)O)=O)C=C1

• Molecular Formula :

  C29H34F2N2O2S

• Molecular Weight :

  512.65

• References & Citations :

  [1]Okorom AV, et al. Modifications to 1- (4- (2-Bis (4-fluorophenyl) methyl) sulfinyl) alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile. J Med Chem. 2023 Dec 20.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported