DAT-IN-1

• Description:

  DAT-IN-1 (Coumpound 12b) is an atypical DAT inhibitor with a Ki of 8.37 nM. DAT-IN-1 can be used in the study of psychostimulant use disorder (PSUD) [1].

• UNSPSC:

  12352005

• Target:

  Dopamine Transporter

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dat-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC1=CC=C (C (C2=CC=C (C=C2) F) S (CCN3CCCN (CC3) CC (CC4=CC=CC=C4) O) =O) C=C1

• Molecular Formula:

  C29H34F2N2O2S

• Molecular Weight:

  512.65

• References & Citations:

  [1]Okorom AV, et al. Modifications to 1- (4- (2-Bis (4-fluorophenyl) methyl) sulfinyl) alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile. J Med Chem. 2023 Dec 20.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported