BB-78485

• Description :

  BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1].

• CAS Number :

  [207732-11-4]

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/bb-78485.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](CC1=CC=C2C=CC=CC2=C1)NS(=O)(C3=CC=C4C=CC=CC4=C3)=O)NO

• Molecular Formula :

  C23H20N2O4S

• Molecular Weight :

  420.48

• References & Citations :

  [1]Clements JM, et al. Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002;46 (6) :1793-1799.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported