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BB-3497

CAT: 0804-HY-114900Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-114900Size: 1 Each
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BB-3497 is a potent, orally active and selective peptide deformylase (PDF) inhibitor. BB-3497 is highly selective for PDF (IC50 = 7 nM for E. coli PDF.Ni) over the other mammalian metalloenzymes (MMP-1/2/3/7 and enkephalinase) . BB-3497 exhibits potent activity against gram-positive bacteria and some gram-negative pathogens. BB-3497 protects mice from infection in systemic models of Staphylococeus aureus. BB-3497 can be used for anti-bacterial infection research[1].
CAS Number
[235784-88-0]
UNSPSC
12352211
Target
Antibiotic
Related Pathways
Anti-infection
Field of Research
Infection; Others
Smiles
CCCC[C@@H](C(N[C@@H](C(C)(C)C)C(N(C)C)=O)=O)CN(O)C=O
Molecular Formula
C16H31N3O4
Molecular Weight
329.44
References & Citations
[1]Clements JM, et al. Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. Antimicrob Agents Chemother. 2001 Feb;45 (2) :563-70.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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