Aspidin BB

• Description :

  Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells[1][2].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Bcl-2 Family; Caspase

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/aspidin-bb.html

• Purity :

  98.02

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles :

  CCCC(C1=C(C(C)(C)C(O)=C(CC2=C(O)C(C(CCC)=O)=C(OC)C(C)=C2O)C1=O)O)=O

• Molecular Formula :

  C25H32O8

• Molecular Weight :

  460.52

• References & Citations :

  [1]Sun Y, et al. Aspidin BB, a phloroglucinol derivative, induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. Chem Biol Interact. 2013 Jul 5;204 (2) :88-97.|[2]Chen NH, et al. Drychampones A-C: Three Meroterpenoids from Dryopteris championii. J Org Chem. 2016 Oct 7;81 (19) :9443-9448.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Bax; Bcl-2; Caspase 3

• CAS Number :

  [584-28-1]