BB 0305179

• UNSPSC Description:

  BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bb-0305179.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3

• Molecular Weight:

  311.46

• References & Citations:

  [1]Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28(21):115717.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2512200-83-6