BB 0305179

• Description :

  BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC :

  12352005

• Target :

  Prion Protein

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bb-0305179.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3

• Molecular Formula :

  C21H29NO

• Molecular Weight :

  311.46

• References & Citations :

  [1]Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28 (21) :115717.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2512200-83-6]