BB 0305179

CAT: 0804-HY-147702Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147702Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[2512200-83-6]
UNSPSC
12352005
Target
Prion Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bb-0305179.html
Solubility
10 mM in DMSO
Smiles
O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3
Molecular Formula
C21H29NO
Molecular Weight
311.46
References & Citations
[1]Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28 (21) :115717.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-114900BB-3497
HY-N0310-01Soyasaponin Bb
HY-121021-01BB-78485
HY-177414BB-1701
HY-12244-01BB-22
HY-108164-01Aspidin BB
HY-102009BB-83698
HY-P2799ICreatine Kinase BB (CK-BB), human brain
HY-P7055-01PDGF-BB, Human
HY-P2799C-01Creatine Kinase BB (CK-BB) Isoenzyme, Porcine Brain

Alternative Products

CatalogName
T60775-01BB 0305179

Popular Products