Products for Research Use Only
RegisterLogin

SB 452533

CAT: 0804-HY-108458-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108458-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8[1].
CAS Number
459429-39-1
UNSPSC
12352005
Hazard Statement
H302, H318, H410
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sb-452533.html
Purity
99.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCN(CC)C1=CC=CC(C)=C1)NC2=CC=CC=C2Br
Molecular Formula
C18H22BrN3O
Molecular Weight
376.29
Precautions
H302, H318, H410
References & Citations
[1]Harshad K Rami, et al. Discovery of small molecule antagonists of TRPV1. Bioorg Med Chem Lett. 2004 Jul 16;14 (14) :3631-4.|[2]Parisa Vahidi Ferdowsi, et al. TRPV1 Activation by Capsaicin Mediates Glucose Oxidation and ATP Production Independent of Insulin Signalling in Mouse Skeletal Muscle Cells. Cells. 2021 Jun 21;10 (6) :1560.|[3]Lin Ming Lu, et al. Effect of small dose capsaicin for treatment of pulmonary fibrosis in mice and its mechanism. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2020 May;36 (3) :216-222.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-10666SB-436811
HY-144898-01SB-216
HY-13409-01SB 242084
HY-12043-01SB 525334
HY-112367SB 202474
HY-117574SB 207710
HY-117854SB 201146
HY-135439SB-203186
HY-125082SB 204144
HY-100307SB 247464

Alternative Products

CatalogName
BUP13000-01SB 452533

Popular Products